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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80ee52d98bad76563c7ebe800c0b16cf4d08fbc4e9d92714d4263d3d57c90dd2' 
  AND token = '3HqnU8aibfanSxGkRUvTC4gQDSdCSNIJXFgPw0MPk18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}