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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '808732d0257ee2b684bf525a1c7eeea68b9f2d38aeb806a21304936a66071641' 
  AND token = 'hx5EWNDm8/Z7WSkZ3KT31AEZAOCGoYmWW/vQ6PBu6Xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}