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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48fc73cbf51613c7a32a3bc57b34f95e8ad5578add80792c178f37f1bc70c64f' 
  AND token = '+PIRnil8y5/AxT9+jahgEK035is6KIFHy/x6+kyMtFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}