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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea2a60093afbfd405f06dcecc1e98e0219cb47e163e4d65877c30f6ab4dd4cfc' 
  AND token = '+kRE9/yyQ0W3TDQUvSc5qbNeuw7oQdU+BdKT4/dO4a8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}