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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3dfec45ea769eb2742016161ebd3cc80f740e3e726946e5cc3143d91a5b0da5' 
  AND token = 'wRMqhhyet2nwULM4VF3bITBi65WMR29Aga6Vorb1034=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}