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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5f5547cd5420cc8bb9784fe1e310fad6bd8e55087ca3aeb76afaf1f8fdf17b4' 
  AND token = 'sZqR5cqwQ5XBXqlVoYPnySVBkn9d7urC2KGEE0tnzsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}