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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd2f4e00ee2ed62404caec8b487422b0948c482cfabd0aeafed5b6aebf034d18' 
  AND token = 'AEwM0FXcj7T/PrnyRTtbaX4vjeRM/o5gSJPBP2mQGpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}