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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8618366253f4e9e26696d1191c026c389f5043c55b221ad0bbef7ebdd296f0bb' 
  AND token = '3nLOM6FfjGO+v2i0W2Zw3YPyW8OaGBBstoEAeqLTTII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}