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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db4446977804c42f7df1651ccffea7b8e2d2fa895afcf267728103c4fae07395' 
  AND token = 'PhiANQ7C9pyGeKnr2X2g7PH2JIJp0Gd0Oe2EIicX+bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}