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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73e9f8de10df10da507140f512e29c09fddc767ac9147c7059594924345e9856' 
  AND token = 'h40oAI5uwKcUbDeUkV3zIzt9YRzdLuxZ3OW4a9WPIuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}