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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af0dca05b65f30b2270a0885dfd9f5218e9eb2b3c281e6f4bcbe622a46a889d4' 
  AND token = 'dcW+2devIr53U1e2P4li5jT2SRPKyD8I7i45AySlNCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}