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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edfd2bc26631fe6422a4b04eef3ddd3acdb843818e679141495e9d8b212eaf0f' 
  AND token = 'NNW1lBw8V7H6R1KLe2zw5zWfxwGBLSWbSNZSgzGPujA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}