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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a0065a0136f5313f8ea86526ff00fd8a8e70def4f4c1d340547c9aa02c91c46' 
  AND token = 'QfapCfuGlod4+NJDKClOobfp7Jf6vx/YC6zhYEqVSwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}