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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '740a67108177a8985129a21f7b1626e01ac931380cd4b995a1df3ccec7e1023c' 
  AND token = 'ExV1fyDlsG9lxpSiPqFWjtIV4dtba5ZqA71HX2tP3Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}