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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b5d4d2a8293e564f3b3ae442324d9b5998bb5d7ec1400b566e9d571f4598e91' 
  AND token = 'Z5Ay2/I5kZvseH/PQP1sgQmdP62+nleCAVpFyEuxTc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}