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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca9dd071bee0b90d8732dba2a0082212ccefa6eb57accdfd9340e32be8482dd1' 
  AND token = 'LFr0YePUq9VcrMMbPZ1sUK6sIQygdNo2dp2eH+1JxgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}