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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb0cc5219e54d9e401007d05b20ddfcdf426c931b7bebee37bae79a34d5b170a' 
  AND token = '/3AxjDGxDFU7hlJEYsd22V978MLcQ9QPdcto2Z+aVls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}