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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d4dedb1d7a319aa86929988eaf822da646bc813e0f5e2e678ee647b58710c16' 
  AND token = '7uAfm5FF2LiKDMfqY+KrtJRiXvjP8Ld631PN3cVDE20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}