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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fc4afe3e49079906ba9693803e1da9b6992ec62365f5fd9ab0cfdf813ad5243' 
  AND token = 'bssQe2Rd+BYYiyZBfzYZs4wZHyr8FyoMvVbtWcY36yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}