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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c2344a499e8f447401b4aaad345a0121de485716abf7db5561edc532a0f998' 
  AND token = 'VJUhalWvZdbz2FyE/lxx5abh7Mme4zvNDTSFLTJRKbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}