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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3e9ce31b123fbdece7d3c496211366e23c02219ef8f2ed71774b423ce783d4d' 
  AND token = '+CNXQ+u9SyKCXpIMKDbbLwpn954+J/PTJmx4dFJVtDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}