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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c168d53cc6c977bc5a1ebc423e31b38bfe80cbd932c5b6252279ddbb8e54d607' 
  AND token = '6Z1bV3zMcqj0VcmTNGy6kAtlSMZ14PBUY3pMfzzy2Po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}