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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6542e4ac5a2ad46412448bc87bc9dfcbffe89690b7339f93a600e816a70af46b' 
  AND token = 'O+dcJbmfmCID4OmBvVHhvC7yBp5xDwXzTPTsmmncetg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}