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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8fcc8080d845193ecdcfadf9640a6b94822a380e096727f4a6da7f60d5f982f' 
  AND token = 'JI9PYk6hQ74QhfqNp135TmuoEQvN89v+6y+gxNg20qQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}