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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e1979c459b95f17a65ed933f8feb67c82fe754a06654993a54cf4498a1240a5' 
  AND token = '0Y1HCcfbN7UA+tlLru1PgrrmIjnXI6rxoiOSGoqmpqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}