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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d39839ec38485e48b34120c9b5a0d7d4b4e12a5a43aed27d9659d1c550cad1' 
  AND token = '6ZXrGIuUck1qYZWW/tjI10EQfvpw5DaIuDlZztSRdTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}