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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8a62e6c2241302a2d46e90d700f02d770e2dc95f0a0828a7373354e2986d4c' 
  AND token = 'NQ73RGr7cJGg4f4gaUDKA1Gp+jCyDjTAZxDK/+qhO9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}