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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab5a0a4ad2d88b43f69477422690f64079771978099aeaf548f1b1346b6cc6a0' 
  AND token = '2dyE6poLJdQ69rgvEzO6cAozPRySQCZ49rT8gPl0JxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}