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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a321b7a6ebf616fe8176d40bc78549e0615d87f299fa65b5e3538ce2bc472c7' 
  AND token = 'SLVILQYQascYz86TVbaGPabU11dHQSzr2g/MHhx9lVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}