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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3edcb51107767eb2f45a6abe121f5d56c0e225b5d81b686b420a414a03021d81' 
  AND token = 'grdaNHjtsjjd3EEbQTaIBVRvlw11vK7SD8dzrdOg9zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}