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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a40eaba418734344b734fb660b28a8be73327e97af158057009fa76dbb376355' 
  AND token = 'ipqiQ3EivLH9VYC375JNVfSajyTUK5B4PPk6TLN03Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}