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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efff79a03dc6796e00a9e557a438ded7f3f678db2cd8813d100ea8298ffc759d' 
  AND token = 'zoZwtul2fO4oKsMVznLxCLoXG0C0WoF9Rnku0T2x8So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}