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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d1f9eedaf143e1e17583ddac2e312aede8bd0f74879fc9471b5827d2e612483' 
  AND token = 'Ygn4FHILE1OT/HbtA6lmPUhP4pDYOIkDGHHmGxAps3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}