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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2e0bae115ebda74fbd2a3feeb4cf02b89dc995ba0ed4b364f9b1e8f4cd99637' 
  AND token = 'U+HE7NWi/yGzsxQ3+xwrSpIiqtCYTMdCfzijwC+0iZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}