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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1226e82b54b61525f929ca777f7061654c8dbb68e352b1401d6aac8e48b230d5' 
  AND token = 'a4sEMwHYc4ERjp87gxXbz005dl+RRvZiFIu+6PBoNSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}