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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e118940827ad3d7e814c6c92518d8ece1123beb35ef9043919f2c2ba7f6990d' 
  AND token = 'w1JNG0Fd+pAWgoVOLPvJXKAITl11RJXGRe0/y3LAR3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}