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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64d038d41507c2f66539a7ee932502b96954bdd1d72a9f9a453f07f1e397e774' 
  AND token = 'UfPjb7sBBMPmoIhDLv/6bh/MdtxwuRC+a83E8bGjRrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}