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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e6c2579cd80e19c367b978500354a979a5bf878e20fb49ac0c74624a595a632' 
  AND token = '+huAM7dP+TrvXNX0PGqIZbzAjsPxPqI6JTLcCME5Mqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}