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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed335884b20914dda5d72f2c654a7d36d4cce3cade72280e1a5a7e0e7356ed2e' 
  AND token = 'MWhU/5O7RRYyfqXUuej6mAQoUGmiOgKp78y/YJFNEsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}