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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7df736b6d2d8ee1dc1e3516b138c99c07188910453191e48141ec41be381a6e5' 
  AND token = 'oHgrg6j2vK+jTk24N9xIDYBmNH/hkhewLwbnjN+jQhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}