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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a310d7ed1cba5d801f86c34d86aec2c7986232fe1d9c01d49fb5018f01a6c2aa' 
  AND token = 'wJv6u/MvPckLPSr9xZyZY5uNymYLBaGlcdkLjriirzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}