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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f044a731aaf5c724a0c5aaf1b5302b525775009e90c5d2be5872bd6450aca291' 
  AND token = 'UirImKs/FgcV4dzQ+7Yp2OoVTDaGeXCM8lZVlcMgoGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}