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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd9f1eb4439765a0342db532dc55f78d3d08555a17b0dfe4e77527a56b6289c4' 
  AND token = 'cNbh99V/m9F6SShYKOoQkYIr7+NdYFKUhUsgPWH9JF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}