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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e6b5c273295402533bc29a6098834f5b951f04c86763e4053745f9928741ea9' 
  AND token = 'Qu1aCbLwwZeeD+urBF+U2K2cdlpCU6ftWaeHTKidrV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}