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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f5c17ef93bafa39a999641b10a98442a346bf1e75a989f96c5b57234a4b75b7' 
  AND token = '87LI+tDtMY9kWd1oLKqjcnxni21EMm3wwYSuRBwiAi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}