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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df48e8f714b2e6e12d6d732f1101b1786d9da46b1f0adf394373c4b66d3e6313' 
  AND token = 'slpHGMc7nPUELmNRuS/zIOQRoXGNtu6zFksSPyCKFkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}