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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '297ea94dbc0f30c8e6425fc8aa58f3e5f91dbdfeabc55301a9e21a95b164732f' 
  AND token = 'rlKtqNRWi4PA70cOllYCD5xwRVziGk3Tcejca6b1eyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}