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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12fca32506c5dfb1ebfadbda615d13265a27b25dd8d4b2c914fc404af891c658' 
  AND token = 'Vir/V9BJQuC3rMZL2YNhWlglkovFrQCIuie7Tto2O3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}