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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89021c8531cba9a97f4a79e829ba6c99049c221b8028cde293b3dd0cab021aff' 
  AND token = 'G8caK8+WxoGdMbcCKaX7zkmTrMuxIKXTBYJIF9puVYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}