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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '860c76a6c9582698405e488f955ce09c8836de6c2491bc0143f881a57082d951' 
  AND token = 'TATO5GnIO3gxdSr+TvidN2DDw7dD2dCafcQSgd7Khr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}